The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
- FSH from pituitary ... - LH from pituitary ... LH release from pituitary ... not implant #MenstrualCycle ... #menstruation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
The Hypothalamic-Pituitary-Ovarian ... hypothalamus and anterior pituitary ... hypothalamus and anterior pituitary ... #MenstrualCycle ... HypothalamicPituitary #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... Hyperprolactinemia • Diabetes ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... trauma, iatrogenic, diabetes ... and rigidity Endocrinologic ... hyperlipidemia, diabetes ... (penile artery diameter
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
on the anterior pituitary ... for clarity) #MenstrualCycle ... pathophysiology #Ovulation #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
production by pituitary ... back on anterior pituitary ... production by pituitary ... #MenstrualCycle ... FollicularPhase #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
hypothalamus and anterior pituitary ... Ovarian Cycle #MenstrualCycle ... #LutealPhase #endocrinology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
on the anterior pituitary ... #UterineCycle #MenstrualCycle ... pathophysiology #comparison #endocrinology