The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology ovariancycle growthhormone pituitary comparison diagnosis excess feedbackloop glftap hpoa hypothalamicpituitary macroadenoma masseffects mnemonic overproduction ovulation sideeffects symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... Hormone (GH) Growth ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
sudden +++ positive feedback ... negative to positive feedback ... for clarity) #MenstrualCycle ... pathophysiology #Ovulation #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
#MenstrualCycle ... HypothalamicPituitary #endocrinology ... #feedback
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
#UterineCycle #MenstrualCycle ... pathophysiology #comparison #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology
Menstrual Cycle Physiology: the Uterine Cycle The endometrium has receptors for ovarian hormones! Changes in structure and
fertilized) ovum #MenstrualCycle ... pathophysiology #UterineCycle ... #endocrinology
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