The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy hypersensitivityreaction anaphylaxis xlinked agammaglobulinemia c5c9deficiency complement complications diagnosis gout humoral hyperuricemia immunity inflammation inflammatory management oncogenesis oncology retroviral
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... #Inflammatory #Cascade ... pathophysiology #immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
the complement cascade ... HypersensitivityReaction #Allergy #Immunology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
-> Complement cascade ... pathophysiology #immunology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings #SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
pathophysiology #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
pathophysiology #immunology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
pathophysiology #immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
HypersensitivityReaction #Allergy #Immunology
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
of complement cascade
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
pathophysiology #immunology
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