The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy hypersensitivityreaction anaphylaxis diagnosis xlinked agammaglobulinemia c5c9deficiency cascade childhood complement gonorrhea humoral immunization inflammation inflammatory management oncogenesis oncology pediatrics
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Continued Innate Immunity ... destruction Acquired Immunity ... pathophysiology #immunology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... contribute to immunity ... exposure #Humoral #Immunity ... pathophysiology #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
adaptive humoral immunity ... pathophysiology #immunology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings #SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
pathophysiology #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
pathophysiology #immunology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
pathophysiology #immunology
Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved
impaired local immunity
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
HypersensitivityReaction #Allergy #Immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
HypersensitivityReaction #Allergy #Immunology
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