The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs anaphylaxis complications extraarticular manifestations type1 type4 typei typeiv
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... cells or CTLs -> Inflammation ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Complications: • Acute ... #TypeI #Type1 #HypersensitivityReaction ... #Allergy #Immunology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to a likely allergen ... exposure to known allergen ... in the acute phase ... pathophysiology #immunology
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
• Cardiac - Inflammation ... acute phase reactant ... - Ligamentous inflammation ... lung fibrosis #AnkylosingSpondylitis ... diagnosis #signs #symptoms
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