The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Acute onset of skin ... in the acute phase ... Signs / Symptoms ... pathophysiology #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
X-Linked Agammaglobulinemia ... Signs of immunodeficiency ... humoral immunity Signs ... /Symptoms/Findings ... pathophysiology #immunology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
Orbital Cellulitis ... Panopthalmitis: inflammation ... Blindness #Orbital #Cellulitis ... ophthalmology #diagnosis #signs ... #symptoms
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Periorbital Cellulitis ... Conjunctivitis: inflammation ... localized infection or inflammation ... ophthalmology #diagnosis #signs ... #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... Tissue injury and inflammation ... , Carditis #Acute ... pathophysiology #diagnosis #signs ... #symptoms #complications
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... becomes more severe Signs ... /Symptoms/Complications ... #signs #diagnosis
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... mastoid air cells (inflammation ... mucosa leads to inflammation ... pathophysiology #signs ... #symptoms #diagnosis
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... pathophysiology #diagnosis #symptoms ... #signs #peds #pediatrics
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
• Non-specific Acute-phase ... etc • Systemic inflammation ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
viscosity and inflammation ... trucking" • Acute ... ophthalmology #diagnosis #signs ... #symptoms