The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs benign bph complications extraarticular prostate prostatic ra rheumatoidarthritis ankylosingspondylitis incontinence lupus mastoiditis medications mixed mucocutaneous otology pharmacology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... scaling that extend inflammation ... -> Incr local inflammation ... Mucocutaneous #Manifestations ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... Skin: • Inflammation ... Eyes: • Globe inflammation ... on CXR • RA inflammation ... pathophysiology #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Medications Aging -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic Hyperplasia ... cell nuclei -> Hyperplasia ... smooth-muscle hyperplasia ... Decreased Prostatic inflammation ... #Pharmacology #Urology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic Hyperplasia ... FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... Benign #Prostatic #Hyperplasia ... Pathophysiology #Urology
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
mastoid air cells (inflammation ... mucosa leads to inflammation ... mastoid air cells (inflammation ... pathophysiology #signs #symptoms ... #diagnosis #otology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Extra-articular manifestations ... etc • Systemic inflammation ... pathophysiology #signs #symptoms
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
(neurogenic), inflammation ... Pathophysiology #Signs #Symptoms ... #Urology #Diagnosis
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... • Ocular - Inflammation ... • Cardiac - Inflammation ... Extraarticular #Manifestations ... diagnosis #signs #symptoms
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