The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... cytokines -> localized inflammatory ... Subacute cutaneous lupus ... pathophysiology #diagnosis ... #signs #symptoms
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Mixed Urinary Incontinence ... tumour, stone, BPH ... (neurogenic), inflammation ... Pathophysiology #Signs #Symptoms ... #Urology #Diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... Visual Acuity #CentralRetinalArtery ... ophthalmology #diagnosis ... #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
FGF-related proteins) Inflammation ... activation of inflammatory ... Urgency, nocturia, incontinence ... bladder stones #BPH ... #Diagnosis
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... Bladder and bowel incontinence ... pathophysiology #diagnosis ... #signs #symptoms