The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs symptoms ankylosingspondylitis comparison degenerative extraarticular jointdisease jointpain mucocutaneous sle versus
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... cytokines -> localized inflammatory ... Mucocutaneous #Manifestations ... signs #symptoms #complications
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Swollen Joints • Inflammation ... Rheumatoid arthritis, Lupus ... Extra-articular manifestations ... mild synovial inflammation ... Comparison #Versus #MSK
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... Bladder and bowel incontinence ... #Complications
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