The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... cytokines -> localized inflammatory ... Subacute cutaneous lupus ... Phenomenon #Lupus ... diagnosis #signs #symptoms
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
joint disease Inflammatory ... Swollen Joints • Inflammation ... Rheumatoid arthritis, Lupus ... mild synovial inflammation ... Comparison #Versus #MSK
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... pathophysiology #diagnosis #symptoms ... stages #staging #msk
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... • Cardiac - Inflammation ... lung fibrosis #AnkylosingSpondylitis ... diagnosis #signs #symptoms