The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs complications ankylosingspondylitis benign bph centralretinalartery cholesteatoma crao extraarticular hyperplasia manifestations middleear occlusion ophthalmology otology pediatrics peds prostate
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... destruction), promote inflammation ... cell activity #Inflammatory ... #Cascade #Inflammation ... pathophysiology #immunology
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... severe Signs/Symptoms ... sensorineural is rare • Mastoiditis ... #OtitisMedia #Complications
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... hearing loss, mastoiditis ... mechanisms) #OtitisMedia ... pathophysiology #diagnosis #symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Mastoiditis: Pathogenesis ... clinical findings Acute ... : Extension of inflammatory ... abscesses #Mastoiditis ... pathophysiology #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... trucking" • Acute ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Non-specific Acute-phase ... • Rate of inflammatory ... etc • Systemic inflammation ... pathophysiology #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... Hydronephrosis, Acute ... Urology #Signs #Symptoms
Cholesteatoma (of middle ear): Pathogenesis and clinical findings • Congenital trapping of keratinizing epithelium in middle
middle ear Signs / Symptoms ... Polyp secondary to inflammation ... • Acute otitis ... • Coalescent Mastoiditis ... pathophysiology #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... • Cardiac - Inflammation ... acute phase reactant ... diagnosis #signs #symptoms
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