The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs complications ra rheumatoidarthritis ankylosingspondylitis centralretinalartery lupus mucocutaneous occlusion ophthalmology sle
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... Skin: • Inflammation ... Eyes: • Globe inflammation ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... Artery Occlusion (CRAO ... due to upstream CRAO ... diagnosis #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... cytokines -> localized inflammatory ... -> Incr local inflammation ... Mucocutaneous #Manifestations ... diagnosis #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... endoscopy (Not Inflammatory ... AnkylosingSpondylitis #Extraarticular ... #Manifestations ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Extra-articular manifestations ... • Rate of inflammatory ... etc • Systemic inflammation ... pathophysiology #signs #symptoms
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