The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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hypersensitivityreaction anaphylaxis diagnosis gout hyperuricemia signs symptoms tophi type1 type2 typei
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... cells recruited Complications ... #Immunology #pathophysiology
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
Activation of complement ... space -> Chronic tophaceous ... Hyperuricemia #Pathophysiology ... #Complications ... #Gout #Tophaceous
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... Signs / Symptoms / Complications ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
activates the complement ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
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