The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology
Pathogenesis of Anxiety Disorders

Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... Positive family history ... acid (GABA) #Anxiety ... #Disorders #Pathophysiology
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
(SAD) - Pathophysiology ... negative self evaluations ... perceived negative evaluations ... SocialAnxiety #BehavioralDisorder ... #SAD #Pathophysiology
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... #BehavioralDisorder ... #Pathophysiology
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
idealization and devaluation ... / irritability/anxiety ... experienced BPD Mnemonic ... Signs #Symptoms #Mnemonic
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
You can use the mnemonic ... ideation -> Ex. anxiety ... psychiatry #diagnosis #evaluation ... #mnemonic #aseptic ... #history
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
develop mood and anxiety ... OppositionalDefiant #ODD #BehavioralDisorder ... #Pathophysiology
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
lack of control, history ... Temperament: childhood anxiety ... AnorexiaNervosa #pathophysiology
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
Risk Factors • History ... Appearance over-evaluation ... and experience anxiety ... BulimiaNervosa #pathophysiology
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Mental Status - Anxiety ... clinical diagnosis - History ... Serotonin #Syndrome #Pathophysiology