The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Note: Opioid withdrawal ... combined with withdrawal ... Dysphoric mood, anxiety ... Pathophysiology #Diagnosis #Signs
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
to use EtOH • Withdrawal ... symptoms - ... , seizure, and anxiety ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Psychiatry
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... #BehavioralDisorder ... #signs #psychiatry
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... experienced BPD Mnemonic ... the above with symptoms ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
mood - Incr withdrawal ... - Incr guilt, anxiety ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
anhedonia • Social Anxiety ... familiarity SPD Mnemonic ... reference - Anxiety ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... reduce social anxiety ... of Anxiety: Mind ... SocialAnxiety #BehavioralDisorder ... #signs #psychiatry
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... Symptoms typically ... Alcohol withdrawal ... - Anxiety, insomnia ... Pathophysiology #Diagnosis #Signs
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings
 • Arrogant, Haughty Behaviors or Attitude - Often display
intolerable, causing a withdrawal ... of others NPD Mnemonic ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic