The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms orthopedics psychiatry stages staging acquired adhesivecapsulitis anticonvulsants bonestrength caudaequina cecs chronicexertional compartmentsyndrome complications disruptors femur fracture fractures
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... of allergen-specific ... Allergic reaction ... Stevens-Johnson Syndrome ... #Immunology #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Stevens-Johnson Syndrome ... relapse of bipolar disorder ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... orthopedics #diagnosis #differential ... #causes #pathophysiology
Acquired Disorders of Reduced Bone Strength: Pathogenesis • Hyperparathyroidism • Vitamin D deficiency • Malabsorption syndromes
Acquired Disorders ... Malabsorption syndromes ... Diabetes • Other causes ... #BoneStrength #pathophysiology ... #differential #
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... a stroke that caused ... FrozenShoulder #pathophysiology ... stages #staging #msk
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
Pathogenesis • Bipolar Disorder ... Manic #Secondary #Causes ... #Differential # ... Diagnosis #Pathophysiology
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... activity that causes ... CompartmentSyndrome #CECS #pathophysiology ... signs #symptoms #msk
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... Nerve Palsies • Disordered ... PagetsDisease #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Metabolic / Endocrine disorders ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology
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