The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms hypersensitivityreaction fractures anaphylaxis grades grading injury sports achilles acl acs anterior anteriorcruciateligament causes classification compartmentsyndrome complications differential
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... Complications: • Acute ... #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to known allergen ... symptoms in the acute ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
StressFractures #msk ... #orthopedics #pathophysiology
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments (Acute ... provided, as well as allergy ... Treatments #Management #pathophysiology ... #immunology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... signs #symptoms #msk ... #orthopedics #pathophysiology
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... signs #symptoms #pathophysiology ... #msk #orthopedics
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
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