The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis symptoms syndrome hypersensitivityreaction complications fractures anaphylaxis causes differential grades grading shoulder stages staging achilles acute adhesivecapsulitis agammaglobulinemia anterior bakerscyst
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... #Immunology #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... Syndrome #Diagnosis #pathophysiology ... #signs #symptoms ... #msk
Radiculopathy: Signs and Symptoms • Back/Neck Pain • Decr Range of motion • Abnormal posturing •
Radiculopathy: Signs ... pain Lasegue's sign ... Radiculopathy #MSK ... #diagnosis #signs ... #symptoms #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings Pars interarticularis stress fracture (spondylolysis) - most frequently in the
XR — scotty dog sign ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
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