The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms complications ophthalmology orthopedics pediatrics comparison differential endocrinology genetics injury lupus retinopathy sle stages syndrome 21hydroxylasedeficiency 21ohd acl
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... #Immunization #peds ... #pediatrics #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
Tingling, Burning, Stinging ... , Stabbing) - ... MeralgiaParesthetica #MSK ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
happen at C6/7 Aging ... complications #msk ... #pathophysiology
Radiculopathy: Signs and Symptoms • Back/Neck Pain • Decr Range of motion • Abnormal posturing •
: -> Shooting, stabbing ... Radiculopathy #MSK ... signs #symptoms #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
fractures • Short ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... #differential #causes ... #pathophysiology
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