The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Hypersensitivity #Allergy ... #Allergic #Reactions ... #Types #Classification
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Complications #MSK
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... leading to an allergic ... An allergic reaction ... #Allergic #Reactions ... #Types #Classification
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... #Orthopedics #MSK
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Clinical Findings Classification ... Some sort of end ... #PCL #Injury #MSK ... #Sports #pathophysiology ... #classification
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
> Stiffness is short-lived ... Comparison #Versus #MSK
RICE: Mechanism of Action
Rest (weight bearing or stressful motion discontinued)
Ice (applied to injury)
Compression (wrap applied to
heart) #RICE #Sports ... pathophysiology #mechanism #MSK
Overuse Tendinopathy: Pathogenesis and clinical findings
 • Intrinsic factors: Age, Body weight, Nutrition, Gender, Anatomical variations,
factors: Occupation, Sport ... pathophysiology #msk
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
#ACL #Injury #MSK ... #Sports #pathophysiology