The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs psychiatry complications orthopedics adhesivecapsulitis bulimianervosa causes clinical femoralhead findings frozenshoulder gait genetics knee oa osteoarthritis osteomalacia pagetsdisease
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk ... pathophysiology #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... lateral hip Signs/Symptoms ... • Non-union of fracture ... #msk #diagnosis ... pathophysiology #signs #symptoms
Osteoarthritis (OA): X-ray features - Joint space narrowing (least specific) - Subchondral Cysts (pockets of
Osteoarthritis (OA): X-ray features ... Subchondral Cysts (pockets ... bone deposits/spurs
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... Spondylolisthesis #MSK ... pathophysiology #signs #symptoms
Rickets and Osteomalacia: Pathogenesis and Clinical Findings • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Rickets and Osteomalacia ... closure => • Short ... Bowed legs • Fractures ... disturbances #Rickets ... diagnosis #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Incr Skeletal fractures ... • Short stature
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes #symptoms ... signs #diagnosis #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... pathophysiology #diagnosis #symptoms ... stages #staging #msk
Anorexia Nervosa: Signs and Symptoms Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
Nervosa: Signs and Symptoms ... psychological/behavioral features ... irritability #AnorexiaNervosa ... diagnosis #signs #symptoms
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
increased risk of fracture ... warmth) GENERAL FEATURES ... binge-purge subtype #AnorexiaNervosa ... diagnosis #signs #symptoms
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