The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis symptoms signs comparison complications endocrinology genetics injury ophthalmology syndrome 21hydroxylasedeficiency 21ohd acl agerelated anteriorcruciateligament caudaequina causes childhood classification discherniations
Falls: Pathogenesis and Complications Poly-pharmacy Disorders affecting movement and balance - Sensory deficits - Neuromuscular degeneration/Cerebrovascular disease -
Neuromuscular degeneration ... Lifestyle #Geriatrics ... #Falls #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
fractures • Short ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... ESR, RF, ANA) Degenerative ... > Stiffness is short-lived ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
C6/7 Aging ->Degeneration ... complications #msk ... #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
• Large lumbar degenerative ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... hepatocellular necrosis & degeneration ... #Immunization #peds ... #pediatrics #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
around the hip • Degeneration ... Trendelenburg #Gait #pathophysiology ... signs #diagnosis #msk
Age Related Macular Degeneration: Pathogenesis and clinical findings Photoreceptor atrophy -> Extracellular debris (drusen) from RPE atrophy/metabolism
Related Macular Degeneration ... - Faded/blind spots ... MacularDegeneration #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
#OtitisMedia #pathophysiology ... symptoms #signs #peds ... #pediatrics
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