The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus (SLE ... Myopathy (Also caused ... Erythematosus #SLE ... #MSK #Musculoskeletal
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... exposed areas -> Scaring ... with keratotic scaling ... hair follicles -> causes ... Phenomenon #Lupus #SLE
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... signs #stages #staging ... #msk
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
days long) • Starts ... See also "Follicular ... See also "Ovulation ... See also "Luteal ... , progesterone causes
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
GCA, SLE, GPA) - ... -> Cherry-red spot ... retinal edema caused
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology