The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
hypercoagulable state ... -> Cherry-red spot ... retinal edema caused ... #pathophysiology ... diagnosis #signs #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... #staging #msk
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology ... diagnosis #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... signs #diagnosis #msk
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... Fluoroquinolones - Causes ... #msk #Staging # ... pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms