The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms complications lupus acute allergic caudaequina classification definitions gastrointestinal hypersensitivity hypersensitivityreaction immunology injury musculoskeletal neurology orthopedics reactions sjogrens
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... complexes • Ex: Systemic ... Lupus Erythematosus ... Stevens-Johnson Syndrome ... Classification #Diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... #Lupus #Erythematosus ... #SLE #Gastrointestinal ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... signs #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... arthritis (RA) or systemic ... lupus erythematosus ... (SLE) Signs / ... Pathophysiology #Diagnosis
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... Bladder retention -> Primarily ... hemicord lesion -> Primarily ... #diagnosis #pathophysiology ... signs #symptoms #msk
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... reflexes) • Urinary ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... #diagnosis #symptoms
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