The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms complications hypersensitivityreaction immunology lupus systemic anticonvulsants classification definitions gastrointestinal hypersensitivity mechanism moodstabilizers musculoskeletal pharmacology primary psychiatry reactions
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Systemic Lupus Erythematosus ... Stevens-Johnson Syndrome ... #Allergic #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... Stevens-Johnson Syndrome
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Systemic Lupus • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Systemic #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Systemic #Lupus #Erythematosus ... #SLE #Gastrointestinal ... Complications #pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... Sjögren's, the syndrome ... systemic lupus erythematosus ... (SLE) Signs / ... #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Stevens-Johnson Syndrome ... #SideEffects #Pathophysiology
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