The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis retinopathy signs symptoms pediatrics peds aids alzheimersdisease caudaequina chronic dementia diabetes diabetic fecal genetics hiv hypertensive incontinence keratoconus
Acquired Immunodeficiency Syndrome (AIDS): Summary of Causes and Ocular Manifestations • Molluscum lesions • Eyelid Kaposi
Immunodeficiency Syndrome ... • Cotton wool spots ... #AIDS #Ocular #Complications ... #ophthalmology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms/Complications ... fractures • Short ... pathophysiology #peds #pediatrics
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Pathogenesis and Complications ... irritable bowel syndrome ... #Incontinence #geriatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... Signs / Symptoms / Complications ... pathophysiology #geriatrics
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Signs / Symptoms / Complications ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
-> Cotton-wool Spots ... -> Elschnig's Spots ... pathophysiology #ophthalmology ... signs #symptoms #complications
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... Signs / Symptoms / Complications ... pathophysiology #ophthalmology
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
-> Neovascular complications ... Prematurity #peds #pediatrics ... pathophysiology #ophthalmology
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