The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms cellulitis complications acute astigmatism chemicalinjury chlamydia closedangle extraarticular glaucoma keratoconus manifestations myopia onchocerciasis opthalmology orbital periorbital psoriaticarthritis retinoblastoma
Age Related Macular Degeneration: Pathogenesis and clinical findings Photoreceptor atrophy -> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... early disease) #AgeRelated ... #MacularDegeneration ... #pathophysiology ... #ophthalmology
Orbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Chemosis: Edema of the bulbar conjunctiva b. Panopthalmitis: inflammation of all
- Impinges on ocular ... Impaired extra-ocular ... Orbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... • Loss of the eye ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs
Trachoma: Pathogenesis and clinical findings • Environmental Factors -> Bacterial infection is encouraged by poor hygiene
Transmission -> Eye-seeking ... from nasal or ocular ... Lubrication • Dry eye ... Trachoma #Chlamydia #pathophysiology ... #ophthalmology
Onchocerciasis “River Blindness”: Pathogenesis and Ocular Manifestations Vectorial Transmission -> Onchocerca volvulus, a parasitic helminth, matures in to
Pathogenesis and Ocular ... Microfilariae enter the eye ... RiverBlindness #pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... detachment • Red Eye ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Periorbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Dacryoadenitis: infection of the lacrimal glands b. Conjunctivitis: inflammation of the
Note: Eye exam ... normal: - extra-ocular ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
present with a red eye ... -> crowding of ocular ... damage & blindness Signs ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Contact lens use • Eye ... > Keratoconus Signs ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Manifestations • Ocular ... visual acuity, eye ... lung fibrosis #AnkylosingSpondylitis ... Complications #pathophysiology ... #diagnosis #signs
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