The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Vasculitis -> Acute ... Complications #pathophysiology ... #signs #symptoms
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... Manifestations ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs
Onchocerciasis “River Blindness”: Pathogenesis and Ocular Manifestations
Vectorial Transmission
-> Onchocerca volvulus, a parasitic helminth, matures in to
Pathogenesis and Ocular ... Manifestations ... RiverBlindness #pathophysiology ... #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... Amsler grid) - Macular ... early disease) #AgeRelated ... MacularDegeneration #pathophysiology ... #ophthalmology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
- Impinges on ocular ... Impaired extra-ocular ... Orbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Ocular - Inflammation ... - Inflammation acute ... lung fibrosis #AnkylosingSpondylitis ... Complications #pathophysiology ... #diagnosis #signs
Retinitis Pigmentosa: Pathogenesis and Ocular Manifestations
 • Inherited mutation of rhodopsin gene -> Mode of inheritance
Pathogenesis and Ocular ... Manifestations ... formation • Macular ... RetinitisPigmentosa #pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... -> crowding of ocular ... damage & blindness Signs ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Extra-articular manifestations ... • Non-specific Acute-phase ... Extra-articular signs ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
normal: - extra-ocular ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs