The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... focal melting) -> Retinopathy ... #Xeropthalmia #pathophysiology ... #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive Retinopathy ... vasoconstrictive • Acute ... #Hypertensive #Retinopathy ... #pathophysiology ... #ophthalmology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Abnormal blood flow ... retinal artery blood flow ... trucking" • Acute ... Occlusion #CRAO #pathophysiology ... #ophthalmology
Aqueous Humor Production and Drainage
 • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
structural integrity of ocular ... Pathway (~60-80 % of flow ... ciliary body -> Flows ... #Pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... -> crowding of ocular ... resistance to the flow ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... reduces blood flow ... Amsler grid) - Macular ... MacularDegeneration #pathophysiology ... #ophthalmology
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Manifestations • Ocular ... - Inflammation acute ... lung fibrosis #AnkylosingSpondylitis ... #Extraarticular ... Complications #pathophysiology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
intra- or peri-ocular ... Decr axoplasmic flow ... OpenAngle #Glaucoma #pathophysiology ... #ophthalmology