The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Acquired Immunodeficiency Syndrome (AIDS): Summary of Causes and Ocular Manifestations
 • Molluscum lesions
 • Eyelid Kaposi
Immunodeficiency Syndrome (AIDS ... of Causes and Ocular ... Keratoconiunctivitis sicca (dry eve ... wool spots #AIDS ... #ophthalmology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... focal melting) -> Retinopathy ... • Loss of the eye ... #Xeropthalmia #pathophysiology ... #ophthalmology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... infarcts from occlusions ... #Diabetic #Retinopathy ... #Diabetes #ophthalmology ... complications #pathophysiology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
all coats of the eye ... - Impinges on ocular ... Impaired extra-ocular ... Orbital #Cellulitis #pathophysiology ... #ophthalmology
Trachoma: Pathogenesis and clinical findings

 • Environmental Factors -> Bacterial infection is encouraged by poor hygiene
Transmission -> Eye-seeking ... from nasal or ocular ... Lubrication • Dry eye ... Trachoma #Chlamydia #pathophysiology ... #ophthalmology
Onchocerciasis “River Blindness”: Pathogenesis and Ocular Manifestations
Vectorial Transmission
-> Onchocerca volvulus, a parasitic helminth, matures in to
Pathogenesis and Ocular ... Microfilariae enter the eye ... RiverBlindness #pathophysiology ... #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive Retinopathy ... Hard Exudates • Occlusion ... #Hypertensive #Retinopathy ... #pathophysiology ... #ophthalmology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Note: Eye exam ... normal: - extra-ocular ... If the eye cannot ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology
Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
Retinopathy of Prematurity ... demand of growing eye ... detachment #Retinopathy ... peds #pediatrics #pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
present with a red eye ... Occurs in small eyes ... -> crowding of ocular ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology