The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... Pathophysiology #diagnosis ... #psychiatry #criteria
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Psychological Symptoms ... PanicDisorder #Anxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
mortality rates of all psychiatric ... binge-purge subtype #AnorexiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
• Cognitive Symptoms ... SocialAnxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... related to complications ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Anorexia Nervosa: Signs and Symptoms
Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
Nervosa: Signs and Symptoms ... irritability #AnorexiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
- Must have >3 symptoms ... months, with >1 symptom ... #Conduct #CD #BehavioralDisorder ... Pathophysiology #diagnosis ... #psychiatry #criteria