The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Achilles Tendon ... findings • The Achilles ... in the body • Achilles ... rupture of the Achilles ... pathophysiology #msk #orthopedics
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
cell-independent Ag: Ags ... such as peptides ... Ags tagged with ... Opsonization: Abs ... Neutralization: Abs
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Enthesitis: Commonly Achilles
Necrotizing Fasciitis: Pathogenesis and Clinical Findings

#NecrotizingFasciitis #pathophysiology #orthopedics
pathophysiology #orthopedics
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as ... prominently in Achilles
The Neuroanatomy and Physiology of Emotion
 • Thalamus
 • Primary and Association Cortices
 • The Prefrontal
Nervous System (ANS ... ) -> The ANS automatically
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
StressFractures #msk #orthopedics
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
inflammatory cells • ANS