The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology antipsychotics cppd disease msk pharmacology pseudogout psychiatry sideeffects signs symptoms acs anteriorcruciateligament classification closedangle compartmentsyndrome complications firstgeneration fractures
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
majority of cases) -> Mechanism ... unknown - Familial chondrocalcinosis ... produced, incr gut ... in bones - Chondrocalcinosis ... seen on x-ray #Chondrocalcinosis
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... local signalling mechanisms ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Open Fractures: Mechanisms ... Typically "inside out ... Complications #MSK #Orthopedics
Second Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antipsychotics: Mechanisms ... Antagonism - Block ACh ... Gut, mouth, eyes ... Cardio-metabolic effects - Mechanism ... SecondGeneration #Mechanisms
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... Block action of ACh ... throughout body (mouth, gut ... bradykinesia/akinesia • Acute ... FirstGeneration #Mechanisms
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis ... Disease - Acute ... to crystals -> Acute ... ) (tends to be out ... e.g., wrist) #Chondrocalcinosis
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... must be ruled out ... bodies, shallow ACD ... Photophobia #Acute
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings • Feeling a "pop" • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... knee is "giving out ... AnteriorCruciateLigament #ACL
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