The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology msk pharmacology psychiatry fractures allergy complications definitions hypersensitivity inhibitors reactions signs symptoms types anticonvulsants antipsychotics differential disruptors femur firstgeneration
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... cell surfaces causes ... causes development ... #Types #Classification ... #Diagnosis #Definitions
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Systemic effect -> Nausea ... MoodStabilizers #Mechanism #SideEffects
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Open #Fractures #Diagnosis ... Complications #MSK #Orthopedics
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Dizziness - Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... Grades #Grading #Orthopedics ... #MSK #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
, and/or limbs caused ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology #diagnosis
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... pathophysiology #diagnosis
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