The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs msk psychiatry complications behavioraldisorder endocrinology hypersensitivityreaction sideeffects ophthalmology pharmacology acute anaphylaxis bulimianervosa criteria etoh fractures inhibitors lupus pediatrics
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... #Immunology #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cause quadriplegia ... hemorrhagic rash; symptoms ... Maternal viremia causes ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
provided, as well as allergy ... Treatments #Management #pathophysiology ... #immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
lateral hip Signs/Symptoms ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
etiology Signs/Symptoms ... diagnosis #signs #symptoms ... #pathophysiology ... #msk #orthopedics
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