The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology signs msk psychiatry anorexianervosa stages staging adhesivecapsulitis antipsychotics bulimianervosa complications femoralhead firstgeneration fracture frozenshoulder mechanisms pagetsdisease pharmacology riskfactors
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk #orthopedics ... pathophysiology #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Avulsion or shearing ... lateral hip Signs/Symptoms ... pathophysiology #signs #symptoms ... #orthopedics
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... (and disruptors ... disrupts local ... #Fracture #Healing ... #Stages #Orthopedics
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... post-inflammatory healing ... post-inflammatory tissue healing ... pathophysiology #diagnosis #symptoms
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Extrapyramidal Symptoms ... • Akathisia - Feeling ... FirstGeneration #Mechanisms #SideEffects
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... / Behavioural Features ... Secrecy surrounding eating ... vomiting Other • Symptoms ... diagnosis #signs #symptoms
Anorexia Nervosa: Signs and Symptoms Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
Nervosa: Signs and Symptoms ... episodes of binge-eating ... without binge eating ... psychological/behavioral features ... diagnosis #signs #symptoms
Anorexia Nervosa: Pathogenesis and Risk Factors Biological Risk Factors • Gender: F > M • Genetics: concordance
Neurobiology: disruptions ... female body as having ... diagnosis #signs #symptoms
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
-> Pathologic fractures ... -> Conductive hearing ... diagnosis #signs #symptoms
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