The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk #orthopedics ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Grade 2 - Rami fracture ... posterior ilium fracture ... #PelvicRing #Fractures ... Grades #Grading #Orthopedics ... complications #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Atypical femur fracture ... #msk #orthopedics ... differential #causes #pathophysiology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings

#SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
SevereCombinedImmunodeficiency #XLinked #pathophysiology ... #immunology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: ... Mechanisms, Clinical Features ... Classification #Open #Fractures ... Complications #MSK #Orthopedics
Clavicular Fracture: Pathogenesis and clinical findings

Group I (69%) - Middle third (mid-shaft)
Group II (29%) - Distal
Clavicular Fracture ... and the site of fracture ... with clavicle fractures ... #Clavicular #Fracture ... Grading #Diagnosis #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Necrotizing Fasciitis: Pathogenesis and Clinical Findings

#NecrotizingFasciitis #pathophysiology #orthopedics
NecrotizingFasciitis #pathophysiology ... #orthopedics
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
#Inflammation #pathophysiology ... #immunology