The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs msk psychiatry rheumatoidarthritis stages staging 21hydroxylasedeficiency 21ohd adhesivecapsulitis bulimianervosa complications diabetes diabeticketoacidosis differential disruptors dka excess extraarticular
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk #orthopedics ... pathophysiology #symptoms
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... in elderly Causes ... #msk #orthopedics ... #differential #causes
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... lateral hip Signs/Symptoms ... • Non-union of fracture ... pathophysiology #signs #symptoms ... #orthopedics
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Acne • Coarse features ... diagnosis #signs #symptoms ... #endocrinology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis (RA ... effusion on CXR • RA ... inflammation tends to cause ... RheumatoidArthritis #RA ... pathophysiology #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis (RA ... Joint diseases features ... • RA affects ... RheumatoidArthritis #RA ... pathophysiology #signs #symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... anion gap until it closes ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... pathophysiology #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... Signs / Symptoms ... Headaches • Nausea ... #SideEffects #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs
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