The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... reaction, Myasthenia Gravis ... , Graves' Disease ... Classification #Diagnosis #Definitions
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
clinical findings Definition ... leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
clinical findings Definition ... mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
cyclist) - APC Grade ... 2.5cm - APC Grade ... ligaments - APC Grade ... auto) - LC Grade ... #Grading #Orthopedics
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity: Definitions ... leading to an allergic ... leading to an allergic ... An allergic reaction ... Classification #Diagnosis #Definitions
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
clinical findings Definition ... HypersensitivityReaction #Allergy
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
#Sports #MSK #orthopedics ... #Grading #Grades
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
clinical findings Definition ... HypersensitivityReaction #Allergy
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Genetics: concordance rates ... body fat) as the definition
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
body fat) as the definition ... purging, high rates