The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy diagnosis classification hypersensitivityreaction immunology msk complications definitions fractures hypersensitivity reactions types genetics gustiloanderson lowanklesprain open pediatrics peds pelvicring
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Type III Hypersensitivity ... Serum sickness Type ... #Types #Classification
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... degranulation, leading ... to an allergic ... Anaphylaxis #TypeI ... #Type1 #HypersensitivityReaction
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... Allergic reaction ... Poison ivy) #TypeIV ... #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... reaction • Type ... reaction • Type ... reaction • Type ... #Types #Classification
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
cyclist) - APC Grade ... 2.5cm - APC Grade ... auto) - LC Grade ... 3 - Type 1 or 2 ... #Grading #Orthopedics
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... sickness #TypeIII #Type3 ... HypersensitivityReaction #Allergy
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Classification: • Type ... comminution • Type ... comminution • Type ... comminution • Type ... Complications #MSK #Orthopedics
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... • Obesity -> Type
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