The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis msk signs symptoms complications immunology classification fractures hypersensitivityreaction psychiatry acute allergic ophthalmology anaphylaxis definitions diabetes fracture grades hypersensitivity
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Target: Allergen ... Hypersensitivity #Allergy ... #Allergic #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... HypersensitivityReaction #Allergy
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk #orthopedics
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... to an allergic ... antigen-surface complex, leading ... to an allergic ... immune reaction, leading
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Tissue edema #Allergic
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification #Grades #Grading ... #Orthopedics #MSK
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy
Necrotizing Fasciitis: Pathogenesis and Clinical Findings #NecrotizingFasciitis #pathophysiology #orthopedics
pathophysiology #orthopedics
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