The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis msk signs symptoms geriatrics peds acs acute alzheimersdisease childhood classification compartmentsyndrome complications constipation dementia differential disruptors endocrinology excess femur
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... subthreshold mechanical loading ... from continued loading ... StressFractures #msk #orthopedics ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
bilateral rami fractures ... Grade 2 - Rami fracture ... Classification #Grades #Grading ... #Orthopedics #MSK ... complications #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... in elderly Causes ... #msk #orthopedics ... #differential #causes ... #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Incr Skeletal fractures ... #genetics #pathophysiology ... #peds #pediatrics
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
within GI and URT causes ... Maternal viremia causes ... vessel collapse leading ... Immunization #peds #pediatrics ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Carpal Tunnel Syndrome ... Acne • Coarse features ... endocrinology #pathophysiology
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment Syndrome ... bleeding tendency/fracture ... CompartmentSyndrome #ACS #pathophysiology ... #orthopedics
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Pathogenesis of Select Causes of Constipation in Adults and in Elderly • Mechanical (ex. Bowel Obstruction,
Pathogenesis of Select Causes ... colonic mucosa, leading ... #constipation #pathophysiology ... #geriatrics
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... Fluoroquinolones - Causes ... #Stages #Orthopedics ... #msk #Staging #pathophysiology
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