The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... spinal artery injury ... function below injury ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... cells -> Tissue injury ... Pancarditis and valvular injury ... , Carditis #Acute ... RheumaticFever #pathophysiology
Acute Otitis Externa (Swimmer’s Ear): Pathogenesis and clinical findings
Pathogens = Pseudomonas aeruginosa (most common opportunistic), Staphylococcus,
Acute Otitis Externa ... hair pins) -> Injury ... #SwimmersEar #pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
trucking" • Acute ... Occlusion #CRAO #pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
vasoconstrictive • Acute ... #Retinopathy #pathophysiology ... #ophthalmology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Inflammation: Incr tissue injury ... Hydronephrosis, Acute ... chronic renal injury ... Hyperplasia #Prostate #Pathophysiology
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Ligament (ACL) Injury ... Feeling a "pop" • Acute ... AnteriorCruciateLigament #ACL #Injury ... #MSK #Sports #pathophysiology
Chemical Eye Injury: Pathogenesis and clinical findings
Exogenous chemical to the eye and/or adnexa
 • Ammonia, sodium
Chemical Eye Injury ... #Eye #Ocular #opthalmology ... #pathophysiology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
ganglion cell injury ... factors, oxidative injury ... OpenAngle #Glaucoma #pathophysiology ... #ophthalmology