The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... endocrinology #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic Hyperplasia ... cell nuclei -> Hyperplasia ... smooth-muscle hyperplasia ... #Prostate #Pathophysiology ... #Pharmacology #Urology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Complications: • Gonadal hypoplasia ... Syndrome #genetics #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic Hyperplasia ... Benign #Prostatic #Hyperplasia ... #Prostate #Pathophysiology ... #Urology #Signs ... #Symptoms #Diagnosis
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
trigger Physical Symptoms ... Psychological Symptoms ... PanicDisorder #Anxiety #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
#Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis