The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms genetics msk ophthalmology 21hydroxylasedeficiency 21ohd achilles allergy childhood classification closedangle endocrinology erythematosus fractures gastrointestinal glaucoma grades hypersensitivityreaction
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Erythematosus #SLE ... Gastrointestinal #Complications ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... Classification #Grades #Grading ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
Acute Otitis Media ... resolve by 72 hours Complications ... #OtitisMedia #pathophysiology ... symptoms #signs #peds ... #pediatrics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
metabolic demand of growing ... -> Neovascular complications ... branching of vessels leading ... #Prematurity #peds ... #pediatrics #pathophysiology
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... signs #symptoms #pathophysiology ... #msk #orthopedics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds ... #pediatrics
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... cells recruited Complications ... : • Acute Asthma ... Allergy #Immunology #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... Increased pressure gradient ... Signs / Symptoms / Complications ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
vessel collapse leading ... #Immunization #peds ... #pediatrics #pathophysiology
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