The Calgary Guide to Understanding Disease @TheCalgaryGuide
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X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings

#SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
SevereCombinedImmunodeficiency #XLinked #pathophysiology ... #immunology
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
#Inflammation #pathophysiology ... #immunology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
#Anaphylaxis #pathophysiology ... #immunology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
#Anaphylaxis #pathophysiology ... #immunology #diagnosis
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Treatments #Management #pathophysiology ... #immunology