The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms psychiatry hypersensitivityreaction pharmacology serotonin sideeffects acquired agammaglobulinemia allergic anaphylaxis bonestrength cecs chronicexertional classification compartmentsyndrome definitions differential disorders endocrinology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Mediator: IgM ... + IgG • Immunological ... Immunological Mediator: IgG ... Stevens-Johnson Syndrome ... Classification #Diagnosis
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... Initial exposure to allergen ... Stevens-Johnson Syndrome ... #Immunology #pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... necrosis factor a inhibitors ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
autoimmune antibodies (IgG ... , rarely IgM) against ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... • Serotonin Syndrome ... SSRI Withdrawal Syndrome ... #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... undetectable levels of IgA ... , IgG, and IgM ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors ... #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Bitemporal hemianopsia IGF ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... endocrinology #pathophysiology
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... (CECS) • Diagnosis ... • Diagnostic ... criteria for CECS ... CompartmentSyndrome #CECS #pathophysiology
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