The Calgary Guide to Understanding Disease @TheCalgaryGuide
904.3K 411 160
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
Contributor Ranks
Latest Searches
9 results
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Secondary hyperthyroidism ... Hyperthyroidism #endocrinology ... #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pseudo-hypopyon • Secondary ... Retinoblastoma #pathophysiology ... #ophthalmology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
#21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
lacrimal sac, secondary ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
• Release of secondary ... #OvarianCycle #pathophysiology ... #comparison #endocrinology
Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
Prematurity #peds #pediatrics ... #pathophysiology ... #ophthalmology
Cataract: Pathogenesis and clinical findings

Increased Age (most common) -> Ultraviolet light, radiation, toxins ->Denaturation and abnormal
meshwork contact -> Secondary ... #cataracts #pathophysiology ... #ophthalmology
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
Secondary Glaucoma ... Findings Open-Angle Secondary ... Closed-Angle Secondary ... #Glaucoma #pathophysiology ... #ophthalmology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
central vision #Secondary ... OpenAngle #Glaucoma #pathophysiology ... #ophthalmology