The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Feedback Loop: Prolactin ... secretion Prolactin ... #PRL #FeedbackLoop ... #endocrinology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
: Pre-formed lgE ... binds allergen, ... ": release the pro-inflammatory ... Complications: • Acute ... #Immunology #pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to known allergen ... symptoms in the acute ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
tumors secrete prolactin ... FSH, TSH, ACTH, PRL ... the exception of prolactin ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments (Acute ... provided, as well as allergy ... Treatments #Management #pathophysiology ... #immunology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
with specific pre-formed ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology